An increased amount of uric acid in the urine often indicates gout, which is a common form of arthritis. This condition is characterized by severe pain and tenderness in the joints, especially those in the toes and ankles. A uric acid test measures the amount of uric acid in the body. Uric acid is a chemical that’s produced when your body breaks down purines. Purines are compounds that enter the bloodstream during the natural breakdown of cells in the body. Gout, Metabolic disorder of purine metabolism. Lesch-Nyhan & Fanconi Syndrome.